Do you think a potential 2012 Republican nominee would be helped or hurt by voting AGAINST Paul Ryan's budget?

Since the plan would never be passed (all the Republicans who voted for it knew that, they just thought the Dems would kill it for them) then yes it could be potentially harmful. But you will have to see what they actually end up passing. If what they pass on entitlement reform is reasonable and messaged well, then yes it will hurt. But if what they pass is terrible also, and people are upset then both Dems and Republicans will try and steer clear of the entitlement issue come 2012.